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B-PHARMACY- Physical Pharmaceutics-I – SEM-III ( PCI SYLLABUS )

Solubility expressions, mechanisms of solute solvent interactions, ideal solubility parameters, solvation & association, quantitative approach to the factors influencing solubility of drugs, diffusion principles in biological systems. Solubility of gas in liquids, solubility of liquids in liquids

aoult’s law, real solutions. Partiallymiscible liquids, Critical solution temperature and applications. Distribution law, its limitations and applications

State of matter, changes in the state of matter, latent heats, vapour pressure, sublimation critical point, eutectic mixtures, gases, aerosols – inhalers, relative humidity, liquid complexes, liquid crystals, glassy states, solidcrystalline, amorphous & polymorphism.

Physicochemical properties of drug molecules : Refractive index, optical rotation, dielectric constant, dipole moment, dissociation constant, determinations and applications

Introduction, Classification of Complexation, Applications, methods of analysis, protein binding, Complexation and drug action, crystalline structures of complexes and thermodynamic treatment of stability constants.

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Also Read:   The Pearson Guide to GPAT & Other Entrance Examination in Pharmacy 2019 (Jan 2018 Paper Included)